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ApoA-IV Monoclonal Antibody, 50ul[BT-MCA0167] Rotator The protein has substantial GAP

SKU: 1014380847

4.3
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ApoA-IV Monoclonal Antibody, 50ul[BT-MCA0167] Rotator The protein has substantial GAPApoliprotein (apo) A IV gene contains 3 exons separated by two introns. A sequence polymorphism has been identified in the 3'UTR of the third exon. The primary translation product is a 396 residue preprotein which after proteolytic processing is secreted its primary site of synthesis, the intestine, in association with chylomicron particles. Although its precise function is not known, apo A IV is a potent activator of lecithin cholesterol

Store: lifelines-uk.org.uk · Domain: lifelines-uk.org.uk

Description

The protein has substantial GAP activity towards several Rho-family GTPases in vitro

MISCELLANEOUS: The chimpanzee and orangutan orthologous proteins do not exist

Alternate splicing of EPN2 results in multiple transcript variants encoding different isoforms

The protein encoded by TP53INP2 (tumor protein p53 inducible nuclear protein 2) promotes autophagy and is essential for proper autophagosome formation and processing

ApoA-IV Monoclonal Antibody, 50ul[BT-MCA0167] Rotator The protein has substantial GAPApoliprotein (apo) A IV gene contains 3 exons separated by two introns. A sequence polymorphism has been identified in the 3'UTR of the third exon. The primary translation product is a 396 residue preprotein which after proteolytic processing is secreted its primary site of synthesis, the intestine, in association with chylomicron particles. Although its precise function is not known, apo A IV is a potent activator of lecithin cholesterol

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