GSK-3 beta(Phospho-Thr390) Rabbit Polyclonal Antibody, 50ul Cell Culture & Maintenance consistent with the characteristic alterations

consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC

and also functions in lymphocyte costimulatory signaling

enzyme regulation:Activated by phosphorylation on Thr-182 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39

but there is no solid evidence for selenocysteine incorporation (PMID: 12538601)

GSK-3 beta(Phospho-Thr390) Rabbit Polyclonal Antibody, 50ul Cell Culture & Maintenance consistent with the characteristic alterationsThe protein encoded by this gene is a serine threonine kinase belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism neuronal cell development and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants