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Aim for adequate protein intake throughout the day, approximately 1.2 to 1.6 grams per kilogram of body weight for most people using these medications

Inability to keep down any fluids for 24 hours or signs of severe dehydration Bloody or black, tarry stools Vomiting blood or material that looks like coffee grounds Severe allergic reactions (difficulty breathing, facial swelling, widespread rash) Symptoms of gallbladder disease (severe right upper abdominal pain, fever, jaundice) Additionally, patients with diabetes taking Zepbound alongside insulin or sulfonylureas should monitor blood glucose closely and contact their provider if experiencing recurrent hypoglycemia (blood sugar below 70 mg/dL), as medication adjustments may be necessary

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Our complete GLP-1 fatigue guide covers management strategies for both medications