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FIGURE 1 Activating the Transient Receptor Potential Vanilloid 1 and Cannabinoid 1 Receptors Acetaminophen is first metabolized to p -aminophenol, which easily crosses the blood-brain barrier and is converted to AM404 by fatty acid amide hydrolase (Hogestatt et al., 2005)

[DOI] [PMC free article] [PubMed] [Google Scholar] 229.Chan W., Krieg R.J., Norkus E.P., Chan J.C.M

The photoreduction of O 2 in chloroplast via photosystemI (PSI) leads to the formation of superoxide ions, which rapidly dismutate to H 2 O 2 spontaneously or by the action of superoxide dismutases (Asada, 1998

Furthermore, the precise molecular mechanism underlying VC is complex and not fully elucidated, and the roles of other regulators in this process should not be precluded (Kurabayashi, 2019)