INTS2 Polyclonal Antibody, 50ul Cell Culture Dishes Cooperates with PPP2CA to protect

Cooperates with PPP2CA to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I

The encoded protein is secreted through the plasma membrane but remains membrane-bound

The tyrosine kinase non receptor 2 may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway

Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2

INTS2 Polyclonal Antibody, 50ul Cell Culture Dishes Cooperates with PPP2CA to protectINTS2 (integrator complex subunit 2) is a subunit of the Integrator complex, which associates with the C terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3 prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690).