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PKR(Phospho Thr258) Polyclonal Antibody, 100ul Contamination Detection & Removal The encoded protein binds scaffold/matrix

SKU: 44215597958

4.4
PLN123.75 PLN150.75

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PKR(Phospho Thr258) Polyclonal Antibody, 100ul Contamination Detection & Removal The encoded protein binds scaffold/matrixThe protein encoded by this gene is a serine threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.

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Description

The encoded protein binds scaffold/matrix attachment region (S/MAR) DNA and is involved in cell cycle regulation| apoptosis| differentiation| the stress response| and regulation of immune genes

ITGAL encodes the integrin alpha L chain

TNS3 seems to be involved in mammary cell migration

the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression

PKR(Phospho Thr258) Polyclonal Antibody, 100ul Contamination Detection & Removal The encoded protein binds scaffold/matrixThe protein encoded by this gene is a serine threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.

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