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SKU: 75079420874
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Availability: InStock
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SKU: 75079420874

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Description

Compared with NPT1 wild type, I269T might have faster conformation changes leading to enhance renal urate export (Sakiyama et al., 2016)

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This reaction occurs when excess iron, in the ferrous form (Fe 2+ ), interacts with H 2 O 2 forming as a consequence the hydroxyl radical, a short-life but highly reactive specie that promotes oxidative DNA damage, denaturation of proteins, and lipid peroxidation [29,30] (Figure 3)

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