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TPX2 Polyclonal Antibody, 50ul Mini dry bath DM plays a central role

SKU: 10992439

4.2
PLN142.00 PLN178.00

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TPX2 Polyclonal Antibody, 50ul Mini dry bath DM plays a central roleSpindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at Thr 288 and protects this residue against dephosphorylation.

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Description

DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site

cellular proliferation

Structurally

FAM111B encodes a protein with a trypsin-like cysteine/serine peptidase domain in the C-terminus

TPX2 Polyclonal Antibody, 50ul Mini dry bath DM plays a central roleSpindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at Thr 288 and protects this residue against dephosphorylation.

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