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IRGM Polyclonal Antibody, 100ul Drug Development and Evaluation The choice of splice sites

SKU: 12047462421

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IRGM Polyclonal Antibody, 100ul Drug Development and Evaluation The choice of splice sitesThis gene encodes a member of the p47 immunity related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis.

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Description

The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors

Maternal plasma CRH probably originates from the placenta

The enzyme has widespread tissue expression and has a role in metabolism

Transcription of this gene is highly inducible in response to many cytokines and hormones

IRGM Polyclonal Antibody, 100ul Drug Development and Evaluation The choice of splice sitesThis gene encodes a member of the p47 immunity related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis.

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