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Raf-1 Polyclonal Antibody, 100ul[BT-AP13533] Polyclonal Antibodies This PTP was found to

SKU: 12212236

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Raf-1 Polyclonal Antibody, 100ul[BT-AP13533] Polyclonal Antibodies This PTP was found toThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

Store: lifelines-uk.org.uk · Domain: lifelines-uk.org.uk

Description

This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis

Following growth factor treatment

Individually blister packed in peel-to-open paper/plastic and plastic/plastic wrappers with printed lot No

some of which encode the same protein

Raf-1 Polyclonal Antibody, 100ul[BT-AP13533] Polyclonal Antibodies This PTP was found toThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

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