CCK-4 Monoclonal Antibody, 100ul Antibody Humanization Mutations in this gene have

Mutations in this gene have been associated with cancer

It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation

This gene encodes an alpha subunit of the heteromeric SEC61 complex| which also contains beta and gamma subunits

The beta cluster contains 16 genes and 3 pseudogenes| each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily

CCK-4 Monoclonal Antibody, 100ul Antibody Humanization Mutations in this gene haveThis gene encodes a member of the receptor protein tyrosine kinase family of proteins that transduce extracellular signals across the cell membrane. The encoded protein lacks detectable catalytic tyrosine kinase activity, is involved in the Wnt signaling pathway and plays a role in multiple cellular processes including polarity and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.