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IGF2 Polyclonal Antibody, 50ul Plasma Proteolytic processing is required to

SKU: 12997732818

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IGF2 Polyclonal Antibody, 50ul Plasma Proteolytic processing is required toThis gene encodes a member of the insulin family of polypeptide growth factors which are involved in development and growth. It is an imprinted gene expressed only from the paternal allele and epigenetic changes at this locus are associated with Wilms tumour Beckwith Wiedemann syndrome rhabdomyosarcoma and Silver Russell syndrome. A read through INS IGF2 gene exists whose 5' region overlaps the INS gene and the 3' region overlaps this gene.

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Description

Proteolytic processing is required to generate a mature subunit

which is a regulatory complex located on the thin filament of the sarcomere

It participates in the formation of the Membrane Attack Complex (MAC)

It is also cleaved by caspase-3 in vitro

IGF2 Polyclonal Antibody, 50ul Plasma Proteolytic processing is required toThis gene encodes a member of the insulin family of polypeptide growth factors which are involved in development and growth. It is an imprinted gene expressed only from the paternal allele and epigenetic changes at this locus are associated with Wilms tumour Beckwith Wiedemann syndrome rhabdomyosarcoma and Silver Russell syndrome. A read through INS IGF2 gene exists whose 5' region overlaps the INS gene and the 3' region overlaps this gene.

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