IGFBP7 Polyclonal Antibody, 50ul Biochemical Reagents This protein forms heterodimers with

This protein forms heterodimers with the gene product of the mutL homolog 1 (MLH1) gene to form the MutL-alpha heterodimer

This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer

SIGLEC5 encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family

In addition| using a separate promoter in an intron in the 3' region| it encodes telokin| a small protein identical in sequence to the C-terminus of myosin light chain kinase| that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments

IGFBP7 Polyclonal Antibody, 50ul Biochemical Reagents This protein forms heterodimers withIGFBP7 encodes a member of the insulin like growth factor (IGF) binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF I and IGF II with relatively low affinity, and belongs to a subfamily of low affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants