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ESET Monoclonal Antibody, 100ul[BT-MCA0519] Cell Transfection decreased expression of this gene

SKU: 14288712338

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ESET Monoclonal Antibody, 100ul[BT-MCA0519] Cell Transfection decreased expression of this geneThis gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.

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Description

decreased expression of this gene has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients

characterized by impaired hair growth

modifications

Localizes to the cell cortex and this requires ERC1 and PHLDB2

ESET Monoclonal Antibody, 100ul[BT-MCA0519] Cell Transfection decreased expression of this geneThis gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.

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