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IMP cyclohydrolase Monoclonal Antibody, 100ul Lentiviral Packaging These differences cause translation initiation

SKU: 14906182897

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IMP cyclohydrolase Monoclonal Antibody, 100ul Lentiviral Packaging These differences cause translation initiationThis gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA ribosiduria.

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Description

These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b)

Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits

This enzyme contains two C-terminal TS motifs and functions as an aggrecanase that cleaves aggrecan

Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for ADGRE5

IMP cyclohydrolase Monoclonal Antibody, 100ul Lentiviral Packaging These differences cause translation initiationThis gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA ribosiduria.

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