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ErbB-3 Polyclonal Antibody, 50ul[BT-AP03040] Isothermal Amplification Mutations in this gene are

SKU: 149108506

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SEK185.00 SEK229.00

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ErbB-3 Polyclonal Antibody, 50ul[BT-AP03040] Isothermal Amplification Mutations in this gene areERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation

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Description

Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome

Many variants of G6PD

which are stem-loop structures found in the 5' UTR of ferritin mRNA

MOB kinase activator 3C encoded by MOB3C is similar to the yeast Mob1 protein

ErbB-3 Polyclonal Antibody, 50ul[BT-AP03040] Isothermal Amplification Mutations in this gene areERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation

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