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PKN Polyclonal Antibody, 100ul Serum suggesting that it may play

SKU: 15679451095

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PKN Polyclonal Antibody, 100ul Serum suggesting that it may playThe protein encoded by PKN1 (protein kinase N1) belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3 phosphoinositide dependent protein kinase 1 (PDPK1 PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The

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Description

suggesting that it may play a role in regulating genes in germ cells

Deficiency in this protein (B-cell linker)has also been shown in some cases of pre-B acute lymphoblastic leukemia

Defects in this gene are a cause of Walker-Warburg syndrome (WWS)

The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities

PKN Polyclonal Antibody, 100ul Serum suggesting that it may playThe protein encoded by PKN1 (protein kinase N1) belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3 phosphoinositide dependent protein kinase 1 (PDPK1 PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The

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