DCTN4 Polyclonal Antibody, 50ul Lentiviral Packaging Required for osteocalcin gene expression

Required for osteocalcin gene expression

Spastic paraplegias are a diverse group of disorders in which the autosomal dominant forms are characterized by progressive| lower extremity spasticity caused by axonal degeneration in the terminal portions of the longest descending and ascending corticospinal tracts

The protein encoded by this gene localizes to the Golgi apparatus to modulate Ras signaling

amenorrhea and disordered steroidogenesis

DCTN4 Polyclonal Antibody, 50ul Lentiviral Packaging Required for osteocalcin gene expressionCould have a dual role in dynein targeting and in ACTR1A Arp1 subunit of dynactin pointed end capping. Could be involved in ACTR1A pointed end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.,Belongs to the dynactin subunit 4 family.,subcellular location: Has a punctate cytoplasmic distribution as well as centrosomal distribution typical of dynactin. Overexpression does not disrupt microtubule organization