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Phospho-Artemis (S516) Polyclonal Antibody, 50ul Gene Editing In unstimulated cells

Phospho-Artemis (S516) Polyclonal Antibody, 50ul Gene Editing In unstimulated cells

Name: Phospho-Artemis (S516) Polyclonal Antibody, 50ul Gene Editing In unstimulated cells
Brand: lifelines-uk.org.uk
SKU: 16682642948
Price: 185.00 USD
Availability: InStock
Rating: 4.6039 (8 reviews)

SKU: 16682642948

4.6

SEK185.00 SEK217.00

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Phospho-Artemis (S516) Polyclonal Antibody, 50ul Gene Editing In unstimulated cellsDCLRE1C encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single strand specific 5' 3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in DCLRE1C can cause Athabascan type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative

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Description

In unstimulated cells

while the carboxy-terminal region is protease sensitive

The gene is highly polymorphic in the human population

and may also play a role in the modulation of mitochondrial membrane potential

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