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MAD1(Phospho Ser428) Polyclonal Antibody, 20ul PCR Series While this locus itself is

SKU: 17196808018

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MAD1(Phospho Ser428) Polyclonal Antibody, 20ul PCR Series While this locus itself isMAD1L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Alternative splicing results in multiple transcript variants.

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Description

While this locus itself is conserved among various species| the paralogs are found only in the genus Homo| and not in the genomes of non-human great apes

Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex

CDH9 encodes a type II classical cadherin from the cadherin superfamily

Mutations in this gene cause a potentially fatal autoinflammatory syndrome in human patients

MAD1(Phospho Ser428) Polyclonal Antibody, 20ul PCR Series While this locus itself isMAD1L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Alternative splicing results in multiple transcript variants.

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