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Nkx-2.8 Polyclonal Antibody, 50ul Contamination Detection & Removal The Fos gene family consists

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Nkx-2.8 Polyclonal Antibody, 50ul Contamination Detection & Removal The Fos gene family consistsThe protein encoded by this gene is a homeobox containing developmental regulator associated with liver development. The encoded protein binds to the alpha fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung

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Description

The Fos gene family consists of 4 members: FOS| FOSB| FOSL1| and FOSL2

which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses

The YTH domain is usually located in the middle of the protein sequence and may function in binding to RNA

A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B

Nkx-2.8 Polyclonal Antibody, 50ul Contamination Detection & Removal The Fos gene family consistsThe protein encoded by this gene is a homeobox containing developmental regulator associated with liver development. The encoded protein binds to the alpha fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung

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