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Btk Polyclonal Antibody, 100ul[BT-AP01005] Insect Expression possibly acting as a bridging

SKU: 17908365015

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Btk Polyclonal Antibody, 100ul[BT-AP01005] Insect Expression possibly acting as a bridgingThe protein (Bruton tyrosine kinase) encoded by BTK plays a crucial role in B cell development. Mutations in this gene cause X linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.

Store: lifelines-uk.org.uk · Domain: lifelines-uk.org.uk

Description

possibly acting as a bridging factor between U5 and U4/U6 snRNPs in formation of the spliceosome

Present in T-cells but not B-cells (at protein level)

There are multiple components involved in the NER pathway| including Xeroderma pigmentosum (XP) A-G and V| Cockayne syndrome (CS) A and B| and trichothiodystrophy (TTD) group A| etc

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Btk Polyclonal Antibody, 100ul[BT-AP01005] Insect Expression possibly acting as a bridgingThe protein (Bruton tyrosine kinase) encoded by BTK plays a crucial role in B cell development. Mutations in this gene cause X linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.

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