Neu Polyclonal Antibody, 100ul[BT-AP05905] Human Genome Knockout Libraries Pseudogenes of this gene are

Pseudogenes of this gene are located on the long arm of chromosome 13 and the short arm of chromosome 19

hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19

This growth factor lacks the N-terminal signal sequence present in most of the FGF family members

This gene encodes a protein that is required for Notch pathway signaling| and for the activity and accumulation of gamma-secretase

Neu Polyclonal Antibody, 100ul[BT-AP05905] Human Genome Knockout Libraries Pseudogenes of this gene areERBB2 encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. Erb b2 receptor tyrosine kinase 2 has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase mediated activation of downstream signalling pathways, such as those involving