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PIAS 3 Polyclonal Antibody, 50ul Metabolic enzymes This protein is a member

SKU: 19321879614

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PIAS 3 Polyclonal Antibody, 50ul Metabolic enzymes This protein is a memberPIAS3 encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. Protein inhibitor of activated STAT 3 functions as a SUMO (small ubiquitin like modifier) E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity.

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Description

This protein is a member of the Stac gene family and contains an N-terminal cysteine-rich domain and two SH3 domains

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Forms a ternary complex with NF2/merlin and GRB2

PAK proteins

PIAS 3 Polyclonal Antibody, 50ul Metabolic enzymes This protein is a memberPIAS3 encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. Protein inhibitor of activated STAT 3 functions as a SUMO (small ubiquitin like modifier) E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity.

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