PABP4 Polyclonal Antibody, 50ul Modification Enzymes The N-terminal portion is transported

The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis

This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4)

and studies in rat suggest that alternative use of the two translation initiation sites results in N-terminally distinct protein isoforms with different subcellular localization

elegans as a component of the Ras signaling pathway

PABP4 Polyclonal Antibody, 50ul Modification Enzymes The N-terminal portion is transportedPoly(A) binding proteins (PABPs) bind to the poly(A) tail present at the 3 prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation induced T cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5 fold. PABPC4 contains 4 RNA binding domains and proline rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be