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Dok-2 Polyclonal Antibody, 100ul[BT-AP02698] Enzyme Activity Assays Deficiencies lead to the skeletal

SKU: 19715705124

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Dok-2 Polyclonal Antibody, 100ul[BT-AP02698] Enzyme Activity Assays Deficiencies lead to the skeletalThe protein encoded by DOK2 (docking protein 2)is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.

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Description

Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia| frequently with sex reversal

The encoded protein mediates degradation of CD4 via its interaction with HIV-1 Vpu

Trichoplusia ni

Protein binding assays determined that bystin binds directly to trophinin and tastin

Dok-2 Polyclonal Antibody, 100ul[BT-AP02698] Enzyme Activity Assays Deficiencies lead to the skeletalThe protein encoded by DOK2 (docking protein 2)is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.

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