p21 Polyclonal Antibody, 100ul[BT-AP12603] Thermal Control The encoded protein may play

The encoded protein may play a role in topographic retinotectal projection and in the regulation of retinal angiogenesis in response to hypoxia

ovary and small intestin

nonsyndromatic deafness

Two alternatively spliced transcript variants have been described for this gene

p21 Polyclonal Antibody, 100ul[BT-AP12603] Thermal Control The encoded protein may playThis gene encodes a potent cyclin dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin cyclin dependent kinase2 or cyclin dependent kinase4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53 dependent cell cycle G1 phase arrest in response to a variety of