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MYCN Polyclonal Antibody, 50ul Molecular Sciences including regulation of iron homeostasis

SKU: 21336842762

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SEK185.00 SEK233.00

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MYCN Polyclonal Antibody, 50ul Molecular Sciences including regulation of iron homeostasisThis gene is a member of the MYC family and encodes a protein with a basic helix loop helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Description

including regulation of iron homeostasis

8 kb repeat

The protein encoded by this gene is a member of the RAS superfamily of small GTPases

and GPIb beta contributes to surface expression of the receptor and participates in transmembrane signaling through phosphorylation of its intracellular domain

MYCN Polyclonal Antibody, 50ul Molecular Sciences including regulation of iron homeostasisThis gene is a member of the MYC family and encodes a protein with a basic helix loop helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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