Human Thioredoxin-interacting Protein, TXNIP ELISA Kit , 96T Adenovirus Packaging chromosome 2 makes up approximately

chromosome 2 makes up approximately 8% of the human genome and contains 237 million bases encoding over 1

This protein may be important for binding dynein to specific cargos including the spindle checkpoint protein BUB3

Involved in ubiquitination of IGF1R

Acts as a ligand for C-C chemokine receptor CCR2 (By similarity)

Human Thioredoxin-interacting Protein, TXNIP ELISA Kit , 96T Adenovirus Packaging chromosome 2 makes up approximatelyMay act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5 induced suppression of CDKN1B stability, blocking the COPS5 mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over expression will induce G0 G1