IMP-3 Monoclonal Antibody, 100ul Monoclonal Antibodies This protein binds to the

This protein binds to the SH3 domains of GRB2| an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras)| via its C-terminal proline-rich sequences| and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2

Alternatively spliced transcript variants encoding different isoforms have been found for ARAF

A related protein in mouse suggests that this protein (armadillo repeat containing 6) has a conserved function

this transcript contains an alternate open reading frame (ARF) that specifies a protein which is structurally unrelated to the products of the other variants

IMP-3 Monoclonal Antibody, 100ul Monoclonal Antibodies This protein binds to theThe protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin like growth factor II leader 3 mRNA and may repress translation of insulin like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative