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RANKL Polyclonal Antibody, 100ul[BT-AP07786] Immunoassays CNKSR2 encodes a multidomain protein

SKU: 22287380751

4.5
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RANKL Polyclonal Antibody, 100ul[BT-AP07786] Immunoassays CNKSR2 encodes a multidomain proteinThis gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss.

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Description

CNKSR2 encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream from Ras

This family member is involved in vesicular transport between endosomes and the trans-Golgi network

Exportin 1 also regulates NFAT and AP-1

|subunit:Heterodimer with the retinoid X receptor

RANKL Polyclonal Antibody, 100ul[BT-AP07786] Immunoassays CNKSR2 encodes a multidomain proteinThis gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss.

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