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BubR1 Polyclonal Antibody, 50ul 3D Culture One of several members of

SKU: 23174830955

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BubR1 Polyclonal Antibody, 50ul 3D Culture One of several members ofBUB1B encodes a kinase involved in spindle checkpoint function. The protein (BUB1 mitotic checkpoint serine threonine kinase B)has been localized to the kinetochore and plays a role in the inhibition of the anaphase promoting complex cyclosome (APC C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.

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Description

One of several members of the Ser/Thr protein kinase family

and reversing their death repressor activity

and a pseudogene of this gene is located on the short arm of chromosome 20

The neurotransmitter serotonin (5-hydroxytryptamine

BubR1 Polyclonal Antibody, 50ul 3D Culture One of several members ofBUB1B encodes a kinase involved in spindle checkpoint function. The protein (BUB1 mitotic checkpoint serine threonine kinase B)has been localized to the kinetochore and plays a role in the inhibition of the anaphase promoting complex cyclosome (APC C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.

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