BubR1 Polyclonal Antibody, 50ul 3D Culture One of several members of
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BubR1 Polyclonal Antibody, 50ul 3D Culture One of several members ofBUB1B encodes a kinase involved in spindle checkpoint function. The protein (BUB1 mitotic checkpoint serine threonine kinase B)has been localized to the kinetochore and plays a role in the inhibition of the anaphase promoting complex cyclosome (APC C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.
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