XRCC3 Polyclonal Antibody, 50ul[BT-AP09625] Enzyme Activity Assays The protein encoded by DNAI2

The protein encoded by DNAI2 (dynein axonemal intermediate chain 2) belongs to the dynein intermediate chain family

Involved in the renal elimination of endogenous and exogenous organic anions

Defects in this gene are associated with a susceptibility to asthma

Thr-312 is likely to be the main autophosphorylation site

XRCC3 Polyclonal Antibody, 50ul[BT-AP09625] Enzyme Activity Assays The protein encoded by DNAI2XRCC3 encodes a member of the RecA Rad51 related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair deficient mutant that exhibits hypersensitivity to a number of different DNA damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying