HMG-14 Polyclonal Antibody, 100ul Capsule Filter Secretogranin-3 encoded by SCG3 is

Secretogranin-3 encoded by SCG3 is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins

Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS)

This gene encodes one of the catalytic subunits of protein kinase A| which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits| in its inactive form

Pseudogenes of this gene have been defined on chromosomes 1| 3| 7| and 8

HMG-14 Polyclonal Antibody, 100ul Capsule Filter Secretogranin-3 encoded by SCG3 isThe high mobility group nucleosome binding domain 1 encoded by HMGN1 binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMG17, the encoded protein may help maintain an open chromatin configuration around transcribable genes.