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CD55 Polyclonal Antibody, 100ul[BT-AP02469] Drug Development and Evaluation The encoded transmembrane protein is

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CD55 Polyclonal Antibody, 100ul[BT-AP02469] Drug Development and Evaluation The encoded transmembrane protein isKRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for KRT18.

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Description

The encoded transmembrane protein is characterized by a type II membrane orientation (has an extracellular C terminus) and the presence of a C-type lectin domain

Based on their distribution patterns| some members of this family are believed to be involved in embryogenesis| spermatogenesis| and cellular growth and division

Allelic variants of SCN1A are associated with generalized epilepsy with febrile seizures and epileptic encephalopathy

This gene encodes a protein belonging to the 14-3-3 family of proteins| members of which mediate signal transduction by binding to phosphoserine-containing proteins

CD55 Polyclonal Antibody, 100ul[BT-AP02469] Drug Development and Evaluation The encoded transmembrane protein isKRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for KRT18.

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