IKK gamma Polyclonal Antibody, 100ul[BT-AP02164] Cell Function Analysis Nuclear receptor interacting protein 1

Nuclear receptor interacting protein 1 (NRIP1) is a nuclear protein that specifically interacts with the hormone-dependent activation domain AF2 of nuclear receptors

but the full-length nature of these variants has not been determined

This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM)

The proline-rich region (PRD) mediates the interaction with COPII coat subunits Sec23/24

IKK gamma Polyclonal Antibody, 100ul[BT-AP02164] Cell Function Analysis Nuclear receptor interacting protein 1This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex which activates NF kappaB resulting in activation of genes involved in inflammation immunity cell survival and other pathways. Mutations in this gene result in incontinentia pigmenti hypohidrotic ectodermal dysplasia and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.