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Rad17 Polyclonal Antibody, 20ul[BT-AP07600] Micro Centrifuge Tubes thought to be involved in

SKU: 26121645346

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Rad17 Polyclonal Antibody, 20ul[BT-AP07600] Micro Centrifuge Tubes thought to be involved inThe protein encoded by RAD17 (RAD17 checkpoint clamp loader component) is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint

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Description

thought to be involved in the stimulation of cell proliferation

The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment

CLCC1 is expressed as four isoforms due to alternative splicing events

and a single representative of the other 3

Rad17 Polyclonal Antibody, 20ul[BT-AP07600] Micro Centrifuge Tubes thought to be involved inThe protein encoded by RAD17 (RAD17 checkpoint clamp loader component) is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint

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