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Rb Polyclonal Antibody, 50ul[BT-AP07688] Custom RNA Oligos In functional expression studies

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Rb Polyclonal Antibody, 50ul[BT-AP07688] Custom RNA Oligos In functional expression studiesThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

In functional expression studies

Lower levels in lung

SLC16A10 is a member of a family of plasma membrane amino acid transporters that mediate the Na(+)-independent transport of aromatic amino acids across the plasma membrane

and deletions at this locus are also associated with a decrease in aminoacylase activity

Rb Polyclonal Antibody, 50ul[BT-AP07688] Custom RNA Oligos In functional expression studiesThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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