Tie-1 Polyclonal Antibody, 100ul Reagent Reservoirs It is proposed to serve

It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity through upstream signaling pathways

The encoded protein may play a role in regulating dendritic cell function

ADGRE2 encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors

The N-terminal half of this protein is required for its centrosome localization and for its multimerization

Tie-1 Polyclonal Antibody, 100ul Reagent Reservoirs It is proposed to serveTIE1 (tyrosine kinase with immunoglobulin like and EGF like domains 1) encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth