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Lamin B1 Polyclonal Antibody, 100ul[BT-AP04935] General Lab Use A pseudogene of this gene

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Lamin B1 Polyclonal Antibody, 100ul[BT-AP04935] General Lab Use A pseudogene of this geneLMNB1 encodes one of the two B type lamin proteins and is a component of the nuclear lamina. A duplication of LMNB1 is associated with autosomal dominant adult onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants.

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Description

A pseudogene of this gene has been defined on chromosome 5

This gene encodes an integral membrane protein that localizes to the endoplasmic reticulum in colonic epithelial cells

This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB

Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance

Lamin B1 Polyclonal Antibody, 100ul[BT-AP04935] General Lab Use A pseudogene of this geneLMNB1 encodes one of the two B type lamin proteins and is a component of the nuclear lamina. A duplication of LMNB1 is associated with autosomal dominant adult onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants.

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