DEN1B Rabbit Polyclonal Antibody, 100ul Stepper The encoded protein localizes to

The encoded protein localizes to the nuclear matrix

These molecules activate latent RNase L

The N-terminal extended form is targeted to the mitochondrion

This gene encodes zinc finger protein| which interacts with a receptor tyrosine kinase involved in the regulation of hematopoietic and lymphoid cells

DEN1B Rabbit Polyclonal Antibody, 100ul Stepper The encoded protein localizes toClathrin (see MIM 118955) mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family such as DENND1B function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein 2 (AP2; see MIM 601024). Thus connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson 2010