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Fhit Polyclonal Antibody, 50ul[BT-AP03232] Electrophoresis & Labeling and erythroid differentiation

SKU: 27298120558

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Fhit Polyclonal Antibody, 50ul[BT-AP03232] Electrophoresis & Labeling and erythroid differentiationFHIT, a member of the histidine triad gene family, encodes a diadenosine 5',5''' P1,P3 triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced

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Description

and erythroid differentiation

The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues

with the highest levels of expression in skeletal muscle and heart

which is associated with the multi-tRNA synthetase complex

Fhit Polyclonal Antibody, 50ul[BT-AP03232] Electrophoresis & Labeling and erythroid differentiationFHIT, a member of the histidine triad gene family, encodes a diadenosine 5',5''' P1,P3 triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced

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