AFF4 Polyclonal Antibody, 20ul Plates & Dishes Studies in rat indicate that

Studies in rat indicate that the protein is translated from a non-AUG translation initiation site

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The protein encoded by the c-mpl gene| CD110| is a 635 amino acid transmembrane domain| with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs

Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position

AFF4 Polyclonal Antibody, 20ul Plates & Dishes Studies in rat indicate thatThe protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5; 11)(q31; q31q23).