KCNK4 (TRAAK) Polyclonal Antibody, 50ul Cryopreservation It highly expressed in the

It highly expressed in the duodenal brush border membrane

Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation

but it has also been detected in the nucleus

It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP)

KCNK4 (TRAAK) Polyclonal Antibody, 50ul Cryopreservation It highly expressed in theThis gene encodes a member of the TWIK related arachidonic acid stimulated two pore potassium channel subfamily. The encoded protein homodimerizes and functions as an outwardly rectifying channel. This channel is regulated by polyunsaturated fatty acids, temperature and mechanical deformation of the lipid membrane. This protein is expressed primarily in neural tissues and may be involved in regulating the noxious input threshold in dorsal root ganglia