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HMG-1 Polyclonal Antibody, 20ul[BT-AP04142] Bacterial Expression Possible role in granule neuron

SKU: 28771607023

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HMG-1 Polyclonal Antibody, 20ul[BT-AP04142] Bacterial Expression Possible role in granule neuronHMGB1 encodes high mobility group protein B1 that belongs to the High Mobility Group box superfamily. The encoded non histone, nuclear DNA binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript

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Description

Possible role in granule neuron development

then this is known to affect dendritic spine morphology and formation---this is thought to occur through the Rac1/PAK1/LIMK/CFL1 pathway

some protein coding and one non-protein coding

which leads to DNA degradation

HMG-1 Polyclonal Antibody, 20ul[BT-AP04142] Bacterial Expression Possible role in granule neuronHMGB1 encodes high mobility group protein B1 that belongs to the High Mobility Group box superfamily. The encoded non histone, nuclear DNA binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript

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