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AKR1CL2 Polyclonal Antibody, 100ul Metabolic enzymes The product of this gene

SKU: 29067156373

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AKR1CL2 Polyclonal Antibody, 100ul Metabolic enzymes The product of this geneAldo keto reductase family 1 member E2 encoded by AKR1E2 is a member of the aldo keto reductase superfamily. Members in this family are characterized by their structure (evolutionarily highly conserved TIM barrel) and function (NAD (P)H dependent oxido reduction of carbonyl groups). Transcripts of this gene have been reported in specimens of human testis. Alternative splicing results in multiple transcript variants.

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Description

The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes

Mediates pleiotropic functions among others in the cardiovascular

Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies

The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway| and transcription of the two genes is coordinately regulated

AKR1CL2 Polyclonal Antibody, 100ul Metabolic enzymes The product of this geneAldo keto reductase family 1 member E2 encoded by AKR1E2 is a member of the aldo keto reductase superfamily. Members in this family are characterized by their structure (evolutionarily highly conserved TIM barrel) and function (NAD (P)H dependent oxido reduction of carbonyl groups). Transcripts of this gene have been reported in specimens of human testis. Alternative splicing results in multiple transcript variants.

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