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CD57 Polyclonal Antibody, 20ul[BT-AP02227] NGS Oligos BCAR3 (breast cancer anti-estrogen resistance

SKU: 29216067472

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CD57 Polyclonal Antibody, 20ul[BT-AP02227] NGS Oligos BCAR3 (breast cancer anti-estrogen resistanceThe corticotropin releasing hormone receptor 2 encoded by CRHR2 belongs to the G protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress

Store: lifelines-uk.org.uk · Domain: lifelines-uk.org.uk

Description

BCAR3 (breast cancer anti-estrogen resistance 3) encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells

while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals

Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction

Temperature range: -80°C–121°C

CD57 Polyclonal Antibody, 20ul[BT-AP02227] NGS Oligos BCAR3 (breast cancer anti-estrogen resistanceThe corticotropin releasing hormone receptor 2 encoded by CRHR2 belongs to the G protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress

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