Beclin-1 Polyclonal Antibody, 20ul[BT-AP14447] Variant Libraries Subunits lacking these cysteine residues

Subunits lacking these cysteine residues are classified as beta-subunits (Groot Kormelink and Luyten| 1997

In vertebrates| this gene is linked in a head-to-head arrangement with the adjacent parkin gene| which is associated with autosomal recessive juvenile Parkinson's disease

Mutations in this gene result in dominant late-onset Fuchs corneal dystrophy

Alternatively spliced transcript variants encoding different isoforms have been found for RAD9A

Beclin-1 Polyclonal Antibody, 20ul[BT-AP14447] Variant Libraries Subunits lacking these cysteine residuesThis gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol 3 kinase (PI3K) complex which mediates vesicle trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.