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GRIP2 Polyclonal Antibody, 20ul Gene Synthesis Smad proteins are phosphorylated and

SKU: 30112671521

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GRIP2 Polyclonal Antibody, 20ul Gene Synthesis Smad proteins are phosphorylated andPDZ 5 mediates the C terminal binding of GRIA2 and GRIA3. PDZ 6 mediates interaction with the PDZ recognition motif of EFNB1. PDZ 7 mediates interaction with CSPG4.,May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons.,Belongs to the GRIP2 family.,Contains 7 PDZ (DHR) domains.,subunit: Interacts with EFNB1,

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Description

Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to TGF-beta signaling

and thus inhibits the synthesis of proinflammatory cytokines

A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism

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GRIP2 Polyclonal Antibody, 20ul Gene Synthesis Smad proteins are phosphorylated andPDZ 5 mediates the C terminal binding of GRIA2 and GRIA3. PDZ 6 mediates interaction with the PDZ recognition motif of EFNB1. PDZ 7 mediates interaction with CSPG4.,May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons.,Belongs to the GRIP2 family.,Contains 7 PDZ (DHR) domains.,subunit: Interacts with EFNB1,

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