ApoER2 Polyclonal Antibody, 50ul Metabolic enzymes tool compounds Three transcript variants encoding the

Three transcript variants encoding the same protein have been found for PTTG1

It is an intronless gene which is downregulated in non-small-cell lung cancer and small-cell lung cancer cell lines| suggesting that it may play a role in lung tumorigenesis

Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP

The encoded protein is a member of the T-box 1 subfamily

ApoER2 Polyclonal Antibody, 50ul Metabolic enzymes tool compounds Three transcript variants encoding theApolipoprotein B48 receptor is a macrophage receptor that binds to the apolipoprotein B48 of dietary triglyceride (TG) rich lipoproteins. This receptor may provide essential lipids, lipid soluble vitamins and other nutrients to reticuloendothelial cells. If overwhelmed with elevated plasma triglyceride, the apolipoprotein B48 receptor may contribute to foam cell formation, endothelial dysfunction, and atherothrombogenesis.